Cancer Research UK – Biotherapeutics Development Facility (BDU) – South Mimms

crukw1Cancer Research UK – Biotherapeutics Development Facility (BDU) – South MimmsThe BDU in South Mimms, Hertfordshire is designed specifically for the production of early phase clinical to cGMP. Biotherapeutics are at the cutting edge of new cancer treatments, and in order to achieve significant advances, the very best and most advanced facilities are required. This replacement for an existing unit is therefore a hugely exciting development for the charity.

The 2,000m² building contains GMP production (mammalian microbial/years, viral technologies), GMP support, final fill process, assay development, QC laboratories, stores, utilities and offices.

The design incorporates significant improvements in personnel and materials flow, equipment reliability, planned maintenance, process efficiency, scheduling, office space, information flow, roles and responsibilities while being versatile scalable and flexible.

The facility includes classified areas of about 300m² on the main production floor with mezzanines for air handling equipment and a basement area for utilities.

The building air leakage test achieved 3.3m³ / hour / m² @ 50pa which is an excellent result as best practice allows this figure to be below 10.

The carbon emissions calculated indicate the building to be an Energy Efficient Building.

Gillian Lewis, Programme Lead said, “Austin was selected to design and engineer this project after an exhaustive selection process, in part because we felt they could match our requirements with a team we could work with.

The successful delivery of the build on-time and ahead of budget has provided a state of the art facility which allows Cancer Research UK to expand research in the years to come.

Austin delivered the development of this building with savings in excess of £1 million.”

The Austin Company is proud and delighted to have won Cancer Research UK’s Best Supplier Award for 2009.

  • architecture
  • mechanical
  • electrical
  • structural
  • public health
  • construction
  • management